Article
An association study of DRD5 with smoking initiation and progression to nicotine dependence.
American journal of medical genetics - 8 Apr 2001
Sullivan P F, Neale M C, Silverman M A, Harris-Kerr C, Myakishev M V, Wormley B, Webb B T, Ma Y, Kendler K S, Straub R E
Abstract excerpt
A large body of genetic epidemiological data strongly implicate genetic factors in the etiology of smoking behavior. Polymorphisms of genes in the dopaminergic system are plausible functional candidate genes and a linkage and an association study suggested that the type 5 dopamine receptor gene (DRD5) may be etiologically involved. We investigated the association of four DRD5 polymorphisms with smoking initiation...
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