Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between the serotonin transporter gene and neuroticism in cigarette smoking behavior.

Molecular psychiatry - 1 Mar 2000

Hu S, Brody C L, Fisher C, Gunzerath L, Nelson M L, Sabol S Z, Sirota L A, Marcus S E, Greenberg B D, Murphy D L, Hamer D H

Abstract excerpt

Cigarette smoking behavior is influenced by both personality traits and inherited factors. Previous research showed that neuroticism-a broad personality domain that includes anxiety, depression, impulsiveness and vulnerability-increases the risk of being a smoker, primarily because of difficulty in quitting. Neuroticism has also been associated with the 5-HTTLPR, a functional polymorphism in the promoter for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Membrane Glycoproteins
Share to Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nerve Tissue Proteins

Share to Neurotic Disorders

Share to Personality

Share to Personality Assessment

Share to Serotonin Plasma Membrane Transport Proteins

Share to Smoking

Source

Identifiers

PMID: 10822346
DOI: 10.1038/sj.mp.4000690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between the serotonin transporter gene and neuroticism in cigarette smoking behavior.PMID 10822346Read ↗

Association of the serotonin transporter gene, neuroticism and smoking behaviours.Semantic proximity Read ↗

Genetic covariation of neuroticism with monoamine oxidase activity and smoking.Semantic proximity Read ↗

Gender differences in association between serotonin transporter gene polymorphism and personality traits.Semantic proximity Read ↗

A genome scan of neuroticism in nicotine dependent smokers.Semantic proximity Read ↗

Neuroticism and polymorphisms in the serotonin transporter gene.Semantic proximity Read ↗

Gender-specific association between serotonin transporter polymorphisms (5-HTTLPR and rs25531) and neuroticism, anxiety and depression in well-defined healthy Han Chinese.Semantic proximity Read ↗

Interacting effects of the serotonin transporter gene and neuroticism in smoking practices and nicotine dependenceSemantic proximity Read ↗

5-HTTLPR moderates effects of current life events on neuroticism: differential susceptibility to environmental influences.Semantic proximity Read ↗

Neuroticism is not associated with the serotonin transporter (5-HTTLPR) polymorphism.Semantic proximity Read ↗

Neuroticism mediates the association of the serotonin transporter gene with lifetime major depression.Semantic proximity Read ↗

CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women.Semantic proximity Read ↗

Family based association analyses between the serotonin transporter gene polymorphism (5-HTTLPR) and neuroticism, anxiety and depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.