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Article

Unraveling Individual Differences In The HIV-1 Transgenic Rat: Therapeutic Efficacy Of Methylphenidate.

Scientific reports - 9 Jan 2018

McLaurin Kristen A, Li Hailong, Booze Rosemarie M, Fairchild Amanda J, Mactutus Charles F

Abstract excerpt

Despite the heterogeneity of HIV-1 associated neurocognitive disorders (HAND), assignment of categorical diagnoses based on the level of impairment (e.g., Frascati criteria) obfuscates the well-acknowledged variability observed within the population of HIV-1+ individuals. The present study sought to elucidate the natural heterogeneity in adult HIV-1 transgenic (Tg) rats using three interrelated aims. First,...

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Identifiers

PMID: 29317696
DOI: 10.1038/s41598-017-18300-2
PMCID: PMC5760575

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