Article
Resistance of Pseudomonas aeruginosa to cefsulodin: modification of penicillin-binding protein 3 and mapping of its chromosomal gene.
The Journal of antimicrobial chemotherapy - 1 Apr 1990
Gotoh N, Nunomura K, Nishino T
Abstract excerpt
Spontaneous cefsulodin-resistant mutants of Pseudomonas aeruginosa PAO4089 were isolated on agar impregnated with 3 mg/l of cefsulodin. This strain does not produce any chromosomal beta-lactamase. The MICs of cefsulodin for the parent and its mutants were 0.78 and 12.5 mg/l, respectively. Complet...
Topics
- Acyltransferases
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Carrier Proteins
- Cefsulodin
- Chromosome Mapping
- Chromosomes, Bacterial
- Crosses, Genetic
- Drug Resistance, Microbial
- Hexosyltransferases
- Microbial Sensitivity Tests
- Multienzyme Complexes
- Muramoylpentapeptide Carboxypeptidase
- Mutation
- Penicillin-Binding Proteins
- Peptidyl Transferases
- Pseudomonas aeruginosa
- beta-Lactamases