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Article

Staphylococcus aureus penicillin-binding protein 4 and intrinsic beta-lactam resistance.

Antimicrobial agents and chemotherapy - 1 Nov 1995

Henze U U, Berger-Bächi B

Abstract excerpt

Increased levels of production of penicillin-binding protein PBP 4 correlated with in vitro acquired intrinsic beta-lactam resistance in a mutant derived from a susceptible strain of Staphylococcus aureus, strain SG511 Berlin. Truncation of the PBP 4 C-terminal membrane anchor abolished the PBP 4 content of cell membrane preparations as well as the resistance phenotype. A single nucleotide change and a...

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Identifiers

PMID: 8585719
DOI: 10.1128/AAC.39.11.2415
PMCID: PMC162958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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