Article
Initiation of in vivo protein synthesis with non-methionine amino acids.
Biochemistry - 8 May 1990
Chattapadhyay R, Pelka H, Schulman L H
Abstract excerpt
Methionine is the universal amino acid for initiation of protein synthesis in all known organisms. The amino acid is coupled to a specific initiator methionine tRNA by methionyl-tRNA synthetase. In Escherichia coli, attachment of methionine to the initiator tRNA (tRNA(fMet)) has been shown to be dependent on synthetase recognition of the methionine anticodon CAU (complementary to the initiation codon AUG),...
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