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Article

An operational RNA code for faithful assignment of AUG triplets to methionine.

Molecular cell - 15 Feb 2008

Jones Thomas E, Brown Cassidy L, Geslain Renaud, Alexander Rebecca W, Ribas de Pouplana Lluís

Abstract excerpt

The assignment of AUG codons to methionine remains a central question of the evolution of the genetic code. We have unveiled a strategy for the discrimination among tRNAs containing CAU (AUG-decoding) anticodons. Mycoplasma penetrans methionyl-tRNA synthetase can directly differentiate between tRNA(Ile)(CAU) and tRNA(Met)(CAU) transcripts (a recognition normally achieved through the modification of anticodon...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18280245
DOI: 10.1016/j.molcel.2007.12.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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