Article
NPR-C gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a multicenter study.
Oncotarget - 7 Jun 2016
Hu Qin, Liu Qiji, Wang Shasha, Zhen Xi, Zhang Zhimian, Lv Ruijuan, Jiang Guihua, Ma Zhiyong, He Hong, Li Daqing, Liu Xiaoling, Gao Fei, Li Jifu, Li Li, Zhang Mei, Ji Xiaoping, Chen Yuguo, Wang Daowen, Huang Dejia, Ma Aiqun, Huang Wei, Zhao Yuxia, Gong Yaoqin, Zhang Cheng, Zhang Yun
Abstract excerpt
To find a new locus that confers significant susceptibility to CAD in Chinese Han population, a genome-wide association study in 200 "extreme individuals" from a Shandong cohort and a pathway-based candidate gene study from a Shanghai cohort (293 CAD/293 controls) were simultaneously performed. Amongst them, 13 SNPs associated with CAD were selected to conduct validation and replication studies in additional 3363...
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