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ALDH2, ADCY3 and BCMO1 polymorphisms and lifestyle-induced traits are jointly associated with CAD risk in Chinese Han people.

Gene - 10 Jan 2022

Ye Cheng-Yin, Xin Jia-Rui, Li Zheng, Yin Xiao-Yu, Guo Shu-Li, Li Jin-Mei, Zhao Tian-Yu, Wang Li, Yang Lei

Abstract excerpt

BACKGROUNDS: To investigate associations of genetic and environmental factors with coronary artery disease (CAD), we collected medical reports, lifestyle details, and blood samples of 2113 individuals, and then used the polymerase chain reaction (PCR)-ligase detection reaction (LDR) to genotype the targeted 102 SNPs. METHODS: We adopted elastic net algorithm to build an association model that considered...

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Adenylyl Cyclases
Aldehyde Dehydrogenase, Mitochondrial
Area Under Curve
Coronary Artery Disease
Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34481002
DOI: 10.1016/j.gene.2021.145948

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