Article
MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2011
Permuth-Wey Jennifer, Chen Zhihua, Tsai Ya-Yu, Lin Hui-Yi, Chen Y Ann, Barnholtz-Sloan Jill, Birrer Michael J, Chanock Stephen J, Cramer Daniel W, Cunningham Julie M, Fenstermacher David, Fridley Brooke L, Garcia-Closas Montserrat, Gayther Simon A, Gentry-Maharaj Aleksandra, Gonzalez-Bosquet Jesus, Iversen Edwin, Jim Heather, McLaughlin John, Menon Usha, Narod Steven A, Phelan Catherine M, Ramus Susan J, Risch Harvey, Song Honglin, Sutphen Rebecca, Terry Kathryn L, Tyrer Jonathan, Vierkant Robert A, Wentzensen Nicolas, Lancaster Johnathan M, Cheng Jin Q, Berchuck Andrew, Pharoah Paul D P, Schildkraut Joellen M, Goode Ellen L, Sellers Thomas A
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNP) in microRNA-related genes have been associated with epithelial ovarian cancer (EOC) risk in two reports, yet associated alleles may be inconsistent across studies. METHODS: We conducted a pooled analysis of previously identified SNPs by combining genotype data from 3,973 invasive EOC cases and 3,276 controls from the Ovarian Cancer Association Consortium. We also...
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