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Article

SNP Regulation of microRNA Expression and Subsequent Colon Cancer Risk.

PloS one - 1 Jan 2015

Mullany Lila E, Wolff Roger K, Herrick Jennifer S, Buas Matthew F, Slattery Martha L

Abstract excerpt

INTRODUCTION: MicroRNAs (miRNAs) regulate messenger RNAs (mRNAs) and as such have been implicated in a variety of diseases, including cancer. MiRNAs regulate mRNAs through binding of the miRNA 5' seed sequence (~7-8 nucleotides) to the mRNA 3' UTRs; polymorphisms in these regions have the potential to alter miRNA-mRNA target associations. SNPs in miRNA genes as well as miRNA-target genes have been proposed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26630397
DOI: 10.1371/journal.pone.0143894
PMCID: PMC4667940

Genes

BRCA1

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