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Article

Predicting cell-specific productivity from CHO gene expression.

Journal of biotechnology - 20 Jan 2011

Clarke Colin, Doolan Padraig, Barron Niall, Meleady Paula, O'Sullivan Finbarr, Gammell Patrick, Melville Mark, Leonard Mark, Clynes Martin

Abstract excerpt

Improving the rate of recombinant protein production in Chinese hamster ovary (CHO) cells is an important consideration in controlling the cost of biopharmaceuticals. We present the first predictive model of productivity in CHO bioprocess culture based on gene expression profiles. The dataset use...

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PMID: 21115077
DOI: 10.1016/j.jbiotec.2010.11.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21115077-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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