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Article

Transcriptional profiling of phenotypically different Epo-Fc expressing CHO clones by cross-species microarray analysis.

Biotechnology journal - 1 Jul 2008

Trummer Evelyn, Ernst Wolfgang, Hesse Friedemann, Schriebl Kornelia, Lattenmayer Christine, Kunert Renate, Vorauer-Uhl Karola, Katinger Hermann, Müller Dethardt

Abstract excerpt

Chinese hamster ovary (CHO) cells exhibit large variabilities regarding growth, recombinant protein production and post-translational processing during cell line development and clone selection. To accelerate the development of stable high quality cell factories, new efficient strategies for cell screening and clone selection are required. In our work, we combined phenotypic characterisation of recombinant CHO...

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Identifiers

PMID: 18481264
DOI: 10.1002/biot.200800038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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