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Article

Both p53 codon 72 Arg/Arg and pro/Arg genotypes in glioblastoma multiforme are associated with a better prognosis in bevacizumab treatment.

BMC cancer - 29 Jul 2020

Shen Chiung-Chyi, Cheng Wen-Yu, Lee Chung-Hsin, Dai Xue-Jun, Chiao Ming-Tsang, Liang Yea-Jiuen, Hsieh Wan-Yu, Mao Tsuo-Fei, Lin Guo-Shi, Chen Shou-Ren, Liu Bai-Shuan, Chen Jun-Peng

Abstract excerpt

BACKGROUND: It has previously been shown that bevacizumab, when added to chemotherapy, improved overall survival in several cancers. In glioblastoma multiforme (GBM), bevacizumab increased progression-free survival and it is widely used for tumor recurrence, though it has failed to improve overall survival (OS) in controlled trials. However, an effective biomarker for predicting the prognosis of bevacizumab...

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Identifiers

PMID: 32727419
DOI: 10.1186/s12885-020-07210-8
PMCID: PMC7391574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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