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Article

Ongoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line.

Molecular and cellular biology - 1 Jun 1990

Kim S, Humphries E H, Tjoelker L, Carlson L, Thompson C B

Abstract excerpt

The chicken immunoglobulin light-chain gene (IgL) encodes only a single variable gene segment capable of recombination. To generate an immune repertoire, chickens diversify this unique rearranged VL gene segment during B-cell development in the bursa of Fabricius. Sequence analysis of IgL cDNAs suggests that both gene conversion events derived from VL segment pseudogene templates (psi VL) and non-template-derived...

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Identifiers

PMID: 2111450
DOI: 10.1128/mcb.10.6.3224-3231.1990
PMCID: PMC360687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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