Article
Somatic diversification of chicken immunoglobulin light chains by point mutations.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990
Parvari R, Ziv E, Lantner F, Heller D, Schechter I
Abstract excerpt
The light-chain locus of chicken has 1 functional V lambda 1 gene, 1 J gene, and 25 pseudo-V lambda-genes (where V = variable and J = joining). A major problem is which somatic mechanisms expand this extremely limited germ-line information to generate many different antibodies. Weill's group [Reynaud, C. A., Anquez, V., Grimal, H. & Weill, J. C. (1987) Cell 48, 379-388] has shown that the pseudo-V lambda-genes...
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