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Article

Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches.

Cell - 8 Mar 1991

Reynaud C A, Mackay C R, Müller R G, Weill J C

Abstract excerpt

Ileal Peyer's patches (IPPs) in the sheep are composed of tightly packed follicles in which surface IgM-positive B cells proliferate and can be exported to the periphery. We report that the light chain rearrangement pattern in a single IPP follicle is much more restricted than in the entire tissue, which indicates that, as in the chicken bursa, ongoing rearrangement does not take place in this organ. Moreover, we...

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Source

Identifiers

PMID: 1900459
DOI: 10.1016/0092-8674(91)90323-q

Genes

IPP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches.PMID 1900459Read ↗

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