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Article

Diversified bursal medullary B cells survive and expand independently after depletion following neonatal infectious bursal disease virus infection

20 Feb 2006

Abstract excerpt

The primary immunoglobulin repertoire of chickens is generated not by gene rearrangement but by a subsequent process of gene conversion in proliferating immature B cells within the follicles of a specialized gut-associated lymphoid organ, the bursa of Fabricius. Neonatal infection with infectious bursal disease virus can eliminate almost the entire bursal B-cell compartment. Thereafter, two types of follicle...

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Identifiers

PMID: 16556270
DOI: 10.1111/j.1365-2567.2006.02332.x

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Diversified bursal medullary B cells survive and expand independently after depletion following neonatal infectious bursal disease virus infectionPMID 16556270Read ↗

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