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Article

Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells.

Nature - 10 May 1990

Bielecki J, Youngman P, Connelly P, Portnoy D A

Abstract excerpt

Intracellular parasites can be classified into those that reside within a host vacuole and those which grow directly in the host cytoplasm. Members of the latter group, which includes Rickettsia, Shigellae, Trypanosoma cruzi, and Listeria monocytogenes, possess haemolytic activity associated with the ability to enter the host cytoplasm. Therefore mutants of L. monocytogenes lacking a pore-forming haemolysin,...

Topics

Bacillus subtilis
Bacterial Toxins
Cell Line
Cloning, Molecular
Cytoplasm
Genes, Bacterial
Heat-Shock Proteins
Hemolysin Proteins
Hemolysis
Listeria monocytogenes
Macrophages

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Electron

Mutation

Promoter Regions, Genetic

Spores, Bacterial

Source

Identifiers

PMID: 2110628
DOI: 10.1038/345175a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2110628-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells.PMID 2110628Read ↗

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