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Article

Regulated translation of listeriolysin O controls virulence of Listeria monocytogenes.

Molecular microbiology - 1 Aug 2006

Schnupf Pamela, Hofmann Jennifer, Norseen Julie, Glomski Ian J, Schwartzstein Hal, Decatur Amy L

Abstract excerpt

Listeria monocytogenes is an intracytosolic bacterial pathogen that escapes from the phagosome using a secreted cytolysin, listeriolysin O (LLO). In the host cytosol, LLO activity is minimized to prevent pore formation in the host plasma membrane; premature lysis of the infected host cell exposes the bacteria to extracellular immune defences of the host and is detrimental to infection. Here we identified...

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Identifiers

PMID: 16859495
DOI: 10.1111/j.1365-2958.2006.05286.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulated translation of listeriolysin O controls virulence of Listeria monocytogenes.PMID 16859495Read ↗

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