Article
Complementation of Listeria seeligeri with the plcA-prfA genes from L. monocytogenes activates transcription of seeligerolysin and leads to bacterial escape from the phagosome of infected mammalian cells.
FEMS microbiology letters - 15 Jan 1997
Karunasagar I, Lampidis R, Goebel W, Kreft J
Abstract excerpt
Infection experiments have shown that the avirulent species Listeria seeligeri invaded the enterocyte-like cell line Caco-2 with low efficiency but was unable to escape from the phagosome. Introduction of the listeriolysin gene (hly) from L. monocytogenes into L. seeligeri via a recombinant plasm...
Topics
- Animals
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- Caco-2 Cells
- Gene Expression Regulation, Bacterial
- Gene Expression Regulation, Enzymologic
- Genes, Bacterial
- Genetic Complementation Test
- Heat-Shock Proteins
- Hemolysin Proteins
- Humans
- Listeria monocytogenes
- Listeriosis