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Article

Experiences with array-based sequence capture; toward clinical applications.

European journal of human genetics : EJHG - 1 Jan 2011

Almomani Rowida, van der Heijden Jaap, Ariyurek Yavuz, Lai Yuching, Bakker Egbert, van Galen Michiel, Breuning Martijn H, den Dunnen Johan T

Abstract excerpt

Although sequencing of a human genome gradually becomes an option, zooming in on the region of interest remains attractive and cost saving. We performed array-based sequence capture using 385K Roche NimbleGen, Inc. arrays to zoom in on the protein-coding and immediate intron-flanking sequences of 112 genes, potentially involved in mental retardation and congenital malformation. Captured material was sequenced...

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Identifiers

PMID: 21102627
DOI: 10.1038/ejhg.2010.145
PMCID: PMC3039511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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