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Article

Array-based sequence capture and next-generation sequencing for the identification of primary immunodeficiencies.

Scandinavian journal of immunology - 1 Mar 2012

Ghosh S, Krux F, Binder V, Gombert M, Niehues T, Feyen O, Laws H-J, Borkhardt A

Abstract excerpt

Primary immunodeficiencies are genetic disorders in which components of immunological pathways are either missing or dysregulated. With the advent of next-generation sequencing, testing for genes in conditions with a heterogeneous genetic background seems more promising. We designed a custom microarray with 385K probe capacity to capture exons of 395 human genes, known or predicted to be associated with primary...

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PMID: 22017423
DOI: 10.1111/j.1365-3083.2011.02658.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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