Article
Clinicopathologic characteristics of ALK rearrangements in primary lung adenocarcinoma with identified EGFR and KRAS status.
Journal of cancer research and clinical oncology - 1 Mar 2014
Wang Jinghui, Dong Yujie, Cai Yiran, Zhou Lijuan, Wu Shafei, Liu Guimei, Su Dan, Li Xi, Qin Na, Nong Jingying, Jia Hongyan, Zhang Quan, Mu Jing, Zeng Xuan, Zhang Haiqing, Zhang Shucai, Zhang Zongde
Abstract excerpt
PURPOSE: EGFR and KRAS genes and ALK arrangements are three genetic drivers of lung adenocarcinoma. The aim of this study was to investigate the clinicopathologic characteristics of the ALK rearrangements in patients with primary lung adenocarcinoma and with identified EGFR or KRAS status. METHOD...
Topics
- Adenocarcinoma
- Adenocarcinoma of Lung
- Adult
- Aged
- Aged, 80 and over
- Anaplastic Lymphoma Kinase
- ErbB Receptors
- Female
- Gene Rearrangement
- Humans
- Immunohistochemistry
- In Situ Hybridization, Fluorescence
- Lung Neoplasms