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Article

Molecular profiling in non-small cell lung cancer: a step toward personalized medicine.

Archives of pathology & laboratory medicine - 1 Apr 2013

Raparia Kirtee, Villa Celina, DeCamp Malcolm M, Patel Jyoti D, Mehta Minesh P

Abstract excerpt

CONTEXT: Lung carcinoma is the result of sequential accumulation of genetic and epigenetic changes. Lung adenocarcinoma is a heterogeneous disease with diverse somatic mutations, and several of them include the so-called driver mutations, which may serve as "druggable" therapeutic targets. Thus, development of personalized approaches for the treatment of non-small cell lung carcinoma (NSCLC) mandates that...

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Identifiers

PMID: 23544937
DOI: 10.5858/arpa.2012-0287-RA

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