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Lessons from Toxoplasma: Host responses that mediate parasite control and the microbial effectors that subvert them

20 Oct 2021

Abstract excerpt

The intracellular parasite Toxoplasma gondii has long provided a tractable experimental system to investigate how the immune system deals with intracellular infections. This review highlights the advances in defining how this organism was first detected and the studies with T. gondii that contribute to our understanding of how the cytokine IFN-γ promotes control of vacuolar pathogens. In addition, the genetic...

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PMID: 34670268
DOI: 10.1084/jem.20201314

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