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Article

Conservation and diversification of dileucine signal recognition by adaptor protein (AP) complex variants.

The Journal of biological chemistry - 21 Jan 2011

Mattera Rafael, Boehm Markus, Chaudhuri Rittik, Prabhu Yogikala, Bonifacino Juan S

Abstract excerpt

The clathrin-associated, heterotetrameric adaptor protein (AP) complexes, AP-1, AP-2, and AP-3, recognize signals in the cytosolic domains of transmembrane proteins, leading to their sorting to endosomes, lysosomes, lysosome-related organelles, and/or the basolateral membrane of polarized epithelial cells. One type of signal, referred to as "dileucine-based," fits the consensus motif (D/E)XXXL(L/I). Previous...

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Identifiers

PMID: 21097499
DOI: 10.1074/jbc.M110.197178
PMCID: PMC3023499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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