Article
A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.
Molecular biology of the cell - 1 Feb 2007
Byland Rahel, Vance Patricia J, Hoxie James A, Marsh Mark
Abstract excerpt
During the assembly of enveloped viruses viral and cellular components essential for infectious particles must colocalize at specific membrane locations. For the human and simian immunodeficiency viruses (HIV and SIV), sorting of the viral envelope proteins (Env) to assembly sites is directed by trafficking signals located in the cytoplasmic domain of the transmembrane protein gp41 (TM). A membrane proximal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
