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Article

Impact of GTF2H1 and RAD54L2 polymorphisms on the risk of lung cancer in the Chinese Han population.

BMC cancer - 16 Nov 2022

Geng Tingting, Li Miao, Chen Rong, Yang Shuangyu, Jin Guoquan, Jin Tinabo, Chen Fulin

Abstract excerpt

BACKGROUND: Repair pathway genes play an important role in the development of lung cancer. The study aimed to assess the correlation between single nucleotide polymorphisms (SNPs) in DNA repair gene (GTF2H1 and RAD54L2) and the risk of lung cancer. METHODS: Five SNPs in GTF2H1 and four SNPs in RAD54L2 in 506 patients with lung cancer and 510 age-and gender-matched healthy controls were genotyped via the Agena...

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Identifiers

PMID: 36384536
DOI: 10.1186/s12885-022-10303-1
PMCID: PMC9670636

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