Article
Genotyping of AAV plasmid stocks: quality control in adeno-associated virus vector production.
Journal of molecular microbiology and biotechnology - 1 Jan 2010
Schmitt Markus, Pawlita Michael, Kleinschmidt Jürgen
Abstract excerpt
Recombinant adeno-associated virus (rAAV) vectors are a promising tool for gene therapy. When multiple serotypes are handled in the same laboratory during the AAV vector production, it is essential to have means to identify the serotype in a sample and to confirm the absence of cross-contaminating AAV sequences in plasmid stocks as well as end products. Here, we describe the development of a Multiplex AAV...
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