Article
The AAV Vector Toolkit: Poised at the Clinical Crossroads
24 Jan 2012
Abstract excerpt
The discovery of naturally occurring adeno-associated virus (AAV) isolates in different animal species and the generation of engineered AAV strains using molecular genetics tools have yielded a versatile AAV vector toolkit. Promising results in preclinical animal models of human disease spurred the much awaited transition toward clinical application, and early successes in phase I/II clinical trials for a broad...
Topics
Join the communities discussing this publication.