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Article

Enhanced excitation-coupled Ca(2+) entry induces nuclear translocation of NFAT and contributes to IL-6 release from myotubes from patients with central core disease.

Human molecular genetics - 1 Feb 2011

Treves Susan, Vukcevic Mirko, Jeannet Pierre-Yves, Levano Soledad, Girard Thierry, Urwyler Albert, Fischer Dirk, Voit Thomas, Jungbluth Heinz, Lillis Sue, Muntoni Francesco, Quinlivan Ros, Sarkozy Anna, Bushby Kate, Zorzato Francesco

Abstract excerpt

Prolonged depolarization of skeletal muscle cells induces entry of extracellular calcium into muscle cells, an event referred to as excitation-coupled calcium entry. Skeletal muscle excitation-coupled calcium entry relies on the interaction between the 1,4-dihydropyridine receptor on the sarcolem...

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Source

Identifiers

PMID: 21088110
DOI: 10.1093/hmg/ddq506

Genes

RYR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21088110-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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