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Article

Dynamic alterations in myoplasmic Ca2+ in malignant hyperthermia and central core disease.

Biochemical and biophysical research communications - 1 Oct 2004

Lyfenko Alla D, Goonasekera Sanjeewa A, Dirksen Robert T

Abstract excerpt

Ca2+ ions play a pivotal role in a wide array of cellular processes ranging from fertilization to cell death. In skeletal muscle, a mechanical interaction between plasma membrane dihydropyridine receptors (DHPRs, L-type Ca2+ channels) and Ca2+ release channels (ryanodine receptors, RyR1s) of the sarcoplasmic reticulum orchestrates a complex, bi-directional Ca2+ signaling process that converts electrical impulses...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15336973
DOI: 10.1016/j.bbrc.2004.08.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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