Article
Association of the wild-type A/A genotype of MBL2 codon 54 with asthma in a North Indian population.
Disease markers - 1 Jan 2012
Birbian Niti, Singh Jagtar, Jindal Surinder Kumar, Joshi Amit, Batra Navneet, Singla Neha
Abstract excerpt
BACKGROUND: High serum MBL level as well as polymorphisms in the mannose-binding lectin 2 (MBL2) gene resulting in MBL deficiency are involved in the mechanism of a number of non-infectious diseases such as asthma, conferring either risk or protection in different population studies. MBL being the first reactant of the MBL pathway is also a major determinant of the fate of the anaphylatoxins such as C3a and C5a,...
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