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Article

Sbds is required for Rac2-mediated monocyte migration and signaling downstream of RANK during osteoclastogenesis.

Blood - 10 Feb 2011

Leung Roland, Cuddy Karl, Wang Yongqiang, Rommens Johanna, Glogauer Michael

Abstract excerpt

Shwachman-Diamond syndrome (SDS) results from mutations in the SBDS gene, characterized by exocrine pancreatic insufficiency and hematologic and skeletal abnormalities. Neutropenia and neutrophil dysfunction are hallmark features of SDS; however, causes for the bone defects are unknown. Dysfuncti...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21084708
DOI: 10.1182/blood-2010-05-282574

Genes

SDS
SBDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21084708-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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