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Article

Polymorphisms in the intermediate region of VacA impact Helicobacter pylori-induced disease development.

Journal of clinical microbiology - 1 Jan 2011

Jones Kathleen R, Jang Sungil, Chang Jennifer Y, Kim Jinmoon, Chung In-Sik, Olsen Cara H, Merrell D Scott, Cha Jeong-Heon

Abstract excerpt

Helicobacter pylori is the etiological agent of diseases such as gastritis, gastric and duodenal ulcers, and two types of gastric cancers. While some insight has been gained into the etiology of these diverse manifestations, by and large, the reason that some individuals develop more severe disease remains elusive. Recent studies have focused on the roles of H. pylori toxins CagA and VacA on the disease process...

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Identifiers

PMID: 21084502
DOI: 10.1128/JCM.01782-10
PMCID: PMC3020468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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