Article
Multiple gene status in Helicobacter pylori strains and risk of gastric cancer development.
Digestion - 1 Jan 2009
Douraghi Masoumeh, Talebkhan Yeganeh, Zeraati Hojjat, Ebrahimzadeh Fatemeh, Nahvijoo Azin, Morakabati Arman, Ghafarpour Masoud, Esmaili Maryam, Bababeik Maryam, Oghalaie Akbar, Rakhshani Nasser, Hosseini Mahmoud Eshagh, Mohagheghi Mohammad Ali, Mohammadi Marjan
Abstract excerpt
BACKGROUND/AIM: The identification of the vacA intermediate region has provided new insights into the role of vacA heterogeneity in relation to gastro-duodenal pathogenesis. The aim of this study was to assess vacA polymorphism in Iranian Helicobacter pylori strains and its association with cagA as a major virulence determinant, gastric histopathology and disease. METHODS: vacA polymorphism and serum antibody...
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