Article
Diversity of VacA intermediate region among Helicobacter pylori strains from several regions of the world.
Journal of clinical microbiology - 1 Mar 2010
Chung Christine, Olivares Asalia, Torres Eugenia, Yilmaz Ozlem, Cohen Henry, Perez-Perez Guillermo
Abstract excerpt
Helicobacter pylori is known to be a major cause of gastric carcinoma and peptic ulceration. cagA positivity and vacA's signal regions and mid-regions are well-characterized markers of H. pylori's virulence. Recently, an intermediate region has been identified as another strong marker of H. pylori-associated disease, and its i1 allele has been linked with severe diseases in colonized hosts. The goal of this study...
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