Article
The association of vacA genotypes and Helicobacter pylori-related gastroduodenal diseases in the Middle East.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Oct 2009
Sugimoto M, Zali M R, Yamaoka Y
Abstract excerpt
The variations in the three regions of the Helicobacter pylori vacA gene, the signal (s1 and s2), intermediate (i1 and i2) and middle regions (m1 and m2), are known to cause the differences in vacuolating activities. However, it was unclear whether these vacA genotypes are associated with the development of gastric cancer and peptic ulcer in the Middle East. The aim was to identify the prevalence of vacA...
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