Article
Association of nonsynonymous substitutions in the intermediate region of the vacA gene of Helicobacter pylori with gastric diseases in Taiwan.
Journal of clinical microbiology - 1 Jan 2009
Sheu Shew-Meei, Hung Kuei-Hsiang, Sheu Bor-Shyang, Yang Hsiao-Bai, Wu Jiunn-Jong
Abstract excerpt
The amino acid sequences corresponding to the vacA intermediate region from 39 isolates of Helicobacter pylori were investigated. The substitution of a G for the third S in the i1-type cluster B sequence (QASEGITSSK) conferred a greater risk of gastric diseases (P < 0.03; Fisher's exact test). Th...
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