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Article

New mechanisms of resistance in Philadelphia chromosome acute lymphoblastic leukemia.

Expert review of hematology - 1 Jun 2009

Martinelli Giovanni, Iacobucci Ilaria, Soverini Simona, Piccaluga Pier Paolo, Cilloni Daniela, Pane Fabrizio

Abstract excerpt

The outcome for adults and children with Philadelphia chromosome acute lymphoblastic leukemia (ALL) has been improved dramatically with the use of tyrosine kinase inhibitors but relapse is an expected event in the majority of patients. We reviewed recent findings obtained from both gene-expression profiling analysis and single nucleotide polymorphism arrays and characterized by the identification of multiple...

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Share to Drug Resistance, Neoplasm
Share to ABL1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BCR gene

Share to Gene Expression Profiling

Share to PAX5 gene

Share to Polymorphism, Single Nucleotide

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Source

Identifiers

PMID: 21082971
DOI: 10.1586/ehm.09.16

Genes

ABL1
BCR
PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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