Article
Mechanisms of drug resistance in acute lymphoblastic leukemia.
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2016
Inukai Takeshi
Abstract excerpt
Outcomes of patients with acute lymphoblastic leukemia (ALL) have improved dramatically with conventional chemotherapy consisting of multiple agents. However, considering the major impact of tyrosine kinase inhibitors in the treatment of Philadelphia chromosome-positive ALL, sensitivities to each chemotherapeutic agent must be appreciated in individual cases to further improve therapeutic outcomes of ALL...
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