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Article

On the spontaneous stochastic dynamics of a single gene: complexity of the molecular interplay at the promoter.

BMC systems biology - 8 Jan 2010

Coulon Antoine, Gandrillon Olivier, Beslon Guillaume

Abstract excerpt

BACKGROUND: Gene promoters can be in various epigenetic states and undergo interactions with many molecules in a highly transient, probabilistic and combinatorial way, resulting in a complex global dynamics as observed experimentally. However, models of stochastic gene expression commonly consider promoter activity as a two-state on/off system. We consider here a model of single-gene stochastic expression that...

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Identifiers

PMID: 20064204
DOI: 10.1186/1752-0509-4-2
PMCID: PMC2832887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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