Article
Quantitative proteomic analysis of tumor reversion in multiple myeloma cells.
Journal of proteome research - 4 Feb 2011
Ge Feng, Zhang Liang, Tao Sheng-Ce, Kitazato Kaio, Zhang Zhi-Ping, Zhang Xian-En, Bi Li-Jun
Abstract excerpt
Tumor reversion is defined as the process by which cancer cells lose their malignant phenotype. However, relatively little is known about the cellular proteome changes that occur during the reversion process. A biological model of multiple myeloma (MM) reversion was established by using the H-1 parvovirus as a tool to select for revertant cells from MM cells. Isolated revertant cells displayed a strongly...
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