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Article

Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus.

Oncotarget - 1 Dec 2015

Kelly Kevin R, Espitia Claudia M, Zhao Weiguo, Wendlandt Erik, Tricot Guido, Zhan Fenghuang, Carew Jennifer S, Nawrocki Steffan T

Abstract excerpt

Despite the development of several new agents for multiple myeloma (MM) therapy over the last decade, drug resistance continues to be a significant problem. Patients with relapsed/refractory disease have high mortality rates and desperately need new precision approaches that directly target specific molecular features that are prevalent in the refractory setting. Reolysin is a proprietary formulation of reovirus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26513296
DOI: 10.18632/oncotarget.5753
PMCID: PMC4747405

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