Article
Development of new adherent mutant from human myeloma-derived cell line: in vitro model of anaplastic transformation of myeloma.
Molecules and cells - 31 Dec 1999
Jung K C, Park C S, Sohn H W, Kook M C, Chung D H, Choi Y K, Hyun B H, Lee I S, Bae Y M, Song H G, Park S H
Abstract excerpt
Anaplastic myeloma is a rare but distinct, biologically aggressive variant of myeloma which usually results from dedifferentiation or anaplastic transformation of the myeloma cells. The molecular mechanisms that determine the biologic behavior of anaplastic myeloma and effective treatment modalities have not been well known due to lack of in vitro models. In the present study, we have developed an anaplastically...
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