Article
Epstein-Barr virus infection leads to partial phenotypic reversion of terminally differentiated malignant B cells.
Cancer letters - 1 Nov 2009
Anastasiadou Eleni, Vaeth Signe, Cuomo Laura, Boccellato Francesco, Vincenti Sara, Cirone Mara, Presutti Carlo, Junker Steffen, Winberg Gösta, Frati Luigi, Wade Paul A, Faggioni Alberto, Trivedi Pankaj
Abstract excerpt
The B cell lymphomas associated with Epstein-Barr virus (EBV) are not limited to any specific stage of B cell differentiation but covers widely different B cell phenotypes. In vitro infection of the virus negative tumors with a recombinant EBV strain has provided important insights into virus-tumor interaction. Here, we investigated the interaction between EBV and terminally differentiated tumor derived B cells,...
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