Article
Molecular features assisting in diagnosis, surgery, and treatment decision making in low-grade gliomas.
Neurosurgical focus - 1 Mar 2015
Chen Ricky, Ravindra Vijay M, Cohen Adam L, Jensen Randy L, Salzman Karen L, Prescot Andrew P, Colman Howard
Abstract excerpt
The preferred management of suspected low-grade gliomas (LGGs) has been disputed, and the implications of molecular changes for medical and surgical management of LGGs are important to consider. Current strategies that make use of molecular markers and imaging techniques and therapeutic considerations offer additional options for management of LGGs. Mutations in the isocitrate dehydrogenase 1 and 2 (IDH1 and...
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