Article
Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance.
Malaria journal - 7 Jan 2010
Marfurt Jutta, Smith Thomas A, Hastings Ian M, Müller Ivo, Sie Albert, Oa Olive, Baisor Moses, Reeder John C, Beck Hans-Peter, Genton Blaise
Abstract excerpt
BACKGROUND: Molecular monitoring of parasite resistance has become an important complementary tool in establishing rational anti-malarial drug policies. Community surveys provide a representative sample of the parasite population and can be carried out more rapidly than accrual of samples from clinical cases, but it is not known whether the frequencies of genetic resistance markers in clinical cases differ from...
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