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Article

Rapid development of colorectal neoplasia in patients with Lynch syndrome.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Apr 2011

Edelstein Daniel L, Axilbund Jennifer, Baxter Melanie, Hylind Linda M, Romans Katharine, Griffin Constance A, Cruz-Correa Marcia, Giardiello Francis M

Abstract excerpt

BACKGROUND & AIMS: Patients with Lynch syndrome have a high risk for colorectal adenomas and carcinomas. We evaluated the development of colorectal neoplasia in these patients. METHODS: We assessed serial colonoscopy findings from 54 persons from 29 pedigrees with pathogenic mutations in MSH2 or...

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Source

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Identifiers

PMID: 21070872
DOI: 10.1016/j.cgh.2010.10.033
PMCID: PMC3073674

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21070872-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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